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Polymorph screening Cocrystal screening Crystallization development IP support

▶ Polymorph screening

发布时间： 2015 - 09 - 19

Guided by the initial crystallization knowledge, we design the relevant experimental space including solvent, temperature, humidity (water activity) etc, systematically employing the highest possible diversity of the screening methods and dimensions to ensure a maximum probability in finding all solid forms. Specific areas including: ◆ Screen all possible solid forms of a new chemical entity ◆ Select the optimum solid form early in drug development ◆ Develop a crystallization process that assure...

▶ Cocrystal screening

发布时间： 2015 - 09 - 19

Pharmaceutical co-crystals are multi-component crystalline structures made of neutral APIs and co-crystal formers that are solid at ambient conditions and that are bound via non-covalent interactions. The co-crystallization of APIs with pharmaceutically acceptable co-crystal formers is nowadays a recognized technique in pharmaceutical science for improving the drug physico-chemical properties leading to an enhanced oral bioavailability. Additionally, co-crystals have great potential in the pharm...

▶ Crystallization development

发布时间： 2015 - 09 - 23

Building on a comprehensive crystallization experiences, we are capable of offering direct support on how to develop robust, reproducible, and scalable crystallization processes that generate the solid with desired crystalline form, size, and shape. Providing strategic crystallization suggestions on how to crystallize out ‘non-crystalline form’ is also one major focus of our crystallization services. Although amorphous form has advantages of greatly enhanced dissolution rate and solubility, crys...

▶ IP support

发布时间： 2015 - 09 - 23

Protecting intellectual property rights is one of the most critical tasks in pharmaceutical R&D. Patent generation formulating an important part of business strategies for both innovative and generic companies. Our services include evaluating all suitable data, determining whether your invention is patentable, and providing suggestions on the scope of protection for potential patent rights.

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